Gut Microbiomes and Early Human Neurodevelopment

This study leverages existing data from the MILk Study (Demerath, PI) to test the hypothesize that variations in microbiome signatures during infancy correlate with differences in hippocampus function, and that early-life events including antibiotic usage may disrupt the microbiome and result in altered memory functions. The results will provide preliminary data for future research to identify mechanisms whereby infant microbiota affect brain function and to develop microbiota modulation strategies to optimize long-term human neurodevelopment.

Direct Costs in 2019: $175,000